So what is messed up?
I stripped out a base screw hole on a M70 and fixed it quite easily by drilling and tapping to the next size (#6).
Got everything I needed from Brownells.
Should hold even better now.
To answer your question, 2 screws may hold ok, but it may help to epoxy bed the base to help stop any movement/flexing.
It is just a 22 cal, but it is one of the very biggest chamberings. A heavy scope will add stress also.
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