I was originally shooting Hornady 55gr varmint ammo. I have had hit coyotes run over 100 yards onto the neighboring property where I cannot recover them. Those are from 250-300 yard shots. Since I switched to 75gr match ammo (had to get a new rifle with a faster twist barrel) and got a custom turret cap (the drop characteristic are very different to 55gr) I have not had this happen again. Wind drift on those 55gr bullets was pretty extreme, going 75gr cut the wind drift in half.