All the actions are the same.
All of the actions are center feed magazine styles. The 22/250 uses a different magazine box than a 308, do to the taper of the shells. I would say that similar taper cartridges would work in that box such as 250 sav, 6.5x47 lapua, 6x47 Lapua, ETC.
I don't know that the center feed magazines will accommodate the 204 Ruger, (I never tried.) The 204 is longer than the 223, and in the old stagged feed magazine system there was two different boxes. Later production they used the 204 Ruger box on the 223's, but I can not say I have seen a 204 centerfeed. I would imagine that the 223 box would be long enough for the 204, but I don't have any experience with it to tell.
All it takes to convert one to another is the magazine assembly. So if you bought a 22/250 set up, and a 308 box set up all you would have to do is switch one out for the other, and so would be the 223.
There is another option. If you are going to use a detachable magazine you could use a "Fred Sled" and single feed any cartridge you would like. If not you can get a single shot follower from SSS, and then single feed any cartridge you like.
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