Action will handle it.
If you go 338, I would HIGHLY recommend the RUM. Will do everything a Lapua does....and not bend you over on the price of brass. You might consider the 338 EDGE as well. 338 on the 300 RUM brass. With the 338 RUM that I built for my shooting buddy, powder capacity with the RUM is not a problem running 300 gr SMK's.
Ah...the 6.5's. Thought of a 6.5x55 or 6.5x55 AI? Built two. Love them. Plenty of mild to expensive brass is available and plentiful. Not sure if I would throat for the 142 AMax's or the Sierra 140/142's. Mine is throated for the Sierra's. Do NOT use the Sierra's on game animals, they are a target bullet and will not do enough damage, at distance, to take a deer down cleanly.
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