Tony,
One concern you may have is using longer bullets will mean using heavier bullets. Your standard Savage 22-250 may have a 12 Twist or a 9 Twist depending on the model. Being able to stabilize the longer and heavier bullets may require a faster twist barrel if you currently have a 12 Twist.

If you have the 12 Twist you may want to have your barrel re-chambered and make sure you get a shorter freebore.

Jim Briggs
NSS