Welcome to the best site on the web! I don't shoot a 22-243AI but I believe it should exceed the 22/250 in performance. 22-250 starting load data should be a good beginning and slowly work up. You may have trouble finding heavy bullet data in 22-250 as most were 1 in 12 or 1 in 14 twist for light varmint bullets. If you plan on using the Berger bullet, contact them on their web site and ask for any load data they may have for their heavy bullets in the 22-250. If they have any data, they will e-mail it to you.
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