Doubt you would see much effect on a varmint centerfire barrel as it's plenty rigid. Since we can tailor our centerfire loads to match what our barrel likes that's the better route to go IMO.
Sporter barrels on the other hand can be a little more fickle due to their being less rigid, thus such a tuner would have a more noticeable effect with getting a specific factory load to shoot better in that barrel. Handloading would still be the better option here was well IMO.
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