For me, based upon more than 6,000 rounds of 6.5mm Creedmoor, the average cost per round is $0.641 per round or 12.82 a box of 20.
Cost of all the factory rounds that I have used for comparison of match ammo to my reloads and to test hunting rounds average out at 1.257 a round.
I've been reloading for lots of years and am approaching 45,000 rounds reloaded in 8 1/2 years so my $1,800 worth of reloading equipment and dies was amortized long ago over that quantity of reloads.

I've been reloading for my 6.5mm Creedmoor rifles for about 2 years and have used premium bullets exclusively - Sierra 123, 140 and 142 SMKs, 130 TMK and 130 TGKs, Berger 140 grain Match, Long Range and Hybrids, Hornady 140 and 147 ELD-Ms.
I use Lapua brass and CCI BR-4 and CCI 400 small rifle primers although I have also used Federal 205M SRPs, and Federal 210M large rifle Match primers.
I use IMR 4451 Enduron or IMR4350 powders primarily because they give me the most accurate results with my rifles. I have also used N150, Reloader 17, and IMR4064 to test accuracy as well.
I load for accuracy, not to save money, so these components are not the cheapest you can find and are probably closer to the high end of the cost spectrum
But I buy do bullets in 500 quantity (actually bought 2,000 140 gr. Hornady ELD-M bullets recently, and powder in 8 lb. batches so I saved some over smaller quantity purchases.
I'm sure a reloader who wants to be frugal could easily save more per round.