If you hand load, the .280 Remington is a fantastic hunting caliber. If you don't hand load, it doesn't offer much that a 7mm-08 can't already do. That's because the factory loads are purposely loaded down for the autoloader Remington that was originally chambered in .280. That's really unfortunate because I'll pick a .280 Rem (with hand loads) over a .270 or '06 every day of the week.

Now that I have an Axis stock and action to play with, the .280 would be the first additional caliber I would build. Great caliber!