Welcome!
I am working all around you in my .260 Rem with H4350 and IMR4451 powders (H4891 is good as well).
Hodgdon gives 43.0 gr of IMR4350 with 140 gr bullets. http://www.hodgdonreloading.com/data/rifle
I can tell you I'm all kinds of happy with the 143 gr Hornady ELD-X as an all-purpose for varmints and targets to whitetail (I have a 1:8" twist). I am hoping to come up with a single load solution for all my .260 Rem shooting. Short to long, little to big (well, 300 lbs big, anyway). It's a beautiful cartridge and worth playing with.
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