I would be inclined to say no, so long as it's done properly and the end result is of good quality. Always easier to sell a good looking gun than one with the finish flaking off of it or with cracks or chips out of the furniture.
I always recommend stripping with a chemical solvent rather than sanding. I like Citri Strip as it's environmentally safe and doesn't smell too God-awful. I use a toothbrush to scrub the finish out of areas with checkering, then when I've got all the finish removed I give the entire stock a good wipe down with mineral spirits and again scrub the checkering with mineral spirits to neutralize and remove any remaining stripper.
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