I have the single shot version, the Model 40, and while I'm extremely pleased with how it shoots, getting cartridges chambered is not exactly easy. Yes, the port is small and guiding rounds made with the ballistic tipped bullets are the worst. It's difficult to align them so they don't get hung up in the barrel recess surrounding the chamber, the conical cut made for extractor clearance. I have to make sure the round enters the chamber before I begin to close the bolt. I suspect the Model 25 has a similar barrel machining surrounding the chamber, so for a person with larger hands, inserting each cartridge into the chamber would really be a challenge. At least feeding from the magazine will aid alignment, but I suspect the shorter and somewhat blunter 35 gr. V-Max and round point "hornet bullets" are what the gun was designed to work with.