I havent shot a 22-250 much. My wife shoots one in a TC Encore and seems to work pretty well. You might wait for some one else to verify what I said but I am pretty sure I am right. I did the same this pretty much. I took a 30:06 ( 270 in the same family) into a 22-243 ( 243 is really close to 250 - .001 base diameter). I am relativly sure that you wont need to change a bolt head. I would wait for some one else chimes in before you buy anything though. I like 2nd opinion's