I've used the .338-06 and .375 Ruger on pronghorn, 200 grain bullets in the .338 and 270 grains in the .375. They worked beautifully and I wouldn't hesitate to use them again. They didn't kill as dramatically as some smaller faster cartridges, but I didn't nearly have the blood shot meat either. Big entrances even bigger edits, no bullets recovered but all the animals were.
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