I have heard of guys using the 125 BTs at full speed in .308s and .30-06s with good results on deer. I use them in a .30-30 AI Contender and they work fine at 2600-2700 fps. The Hornady SSTs are more fragile and may grenade when they hit bone. I also use the 125 BTs in a .30 Herrett Contender pistol, but that velocity is low enough that the bullets certainly work like deer loads.
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