Yes. 2 main differences are. The recoil lug and the primary extraction.
The axis has a loose recoil lug. The 10/110 has a recoil lug under the barrel nut.
The axis primary extraction is between reciever and bolt handle. The 10/110 is between the rear baffle and bolt handle.
The 10/110 is based on the original design. The axis is a value rifle were the manufacturing process has been simplified to make it more affordable. A trip through this sites faq for both wouldn't be a bad idea.
Hope that helps.
Adam.
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