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Though I have stopped wildebeest with 7 x 57, 280 Rem, 308 Win, 30-06, 300 Win Mag, 375 H&H...

The only wildebeest I ever saw escape was one shot with a 338 caliber 250-grain Nosler from a 338 Win Mag. It was hit in the hip and left no blood trail to follow. The medical doctor who shot it then spent the rest of his hunt looking for this wounded wildebeest and being in an unhappy disposition. The wounded wildebeest was ultimately stopped by another hunter using a 7 x 57 with 175-grain solids which produced complete penetration and an instant stop.

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