Yes and no on the bolt handle. There will be no primary extraction with a 110 bolt handle, but people have used them without problems when shooting standard pressure loads.

Barrels interchange with the 1X/11X rifles, and Accutrigger assemblies can be transplanted to the Axis without much doing. Short action bolt head assemblies are the same as those on the Axis, but (if memory serves) bolt bodies are not. Axis magazines with the plastic spring tab are now standard in some 1X/11X rifles like the Trophy Hunter packages, but the older metal floorplate magazines will not. Two-piece scope mounts will also interchange with round top mounts, but one-piece mounts will not.

Stocks are not compatible between Axis and 1X/11X lines. Recoil lugs are also different, though the Axis can be fitted for a standard lug, it is takes a good bit of machining and still requires an Axis stock.