With the exception of the 308 family where you dont see a great deal of improvement AIs rock, faster bullets and less brass growth. Some people have trouble feeding them from magazines, but I have found with my 223AI and 22-250AI that as long as you leave the magazine 1 round short of being jammed full they feed fine, but if you stuff that last round in there it drops the rear of the case and the bolt wont pick it up every time.
My gunsmith is in town this weekend and I will be sending another 22-250 barrel back with him to be rechambered.

Mike