My go to is a trued, tricked, Savage long action with the appropriate barrel and mag changed for the goal at hand. That barrel may be anything from a 17 Fireball all the way to a .50 HPDT (Hammer's Praire Dog Thumper)

Also have a lot of barrels between those 2 extremes.

Can kill anything from the smallest to the largest thing on the planet....even stuff that is now extinct.