I don't own a 220, but if it is similar to a 110/10 rifle, the rear trigger guard screw (that's what you are discussing, correct? You said "rear trigger screw" in the text of your post) does not hold the action in. It only holds in the trigger guard. It is similar to a self-tapping tapered wood screw and screws into the stock material.
If you tried to torque it as tightly as the action screws, you have stripped the hole. You will need to fill the hole with an appropriate material (epoxy, sawdust and glue, etc...) depending on your stock material, redrill a pilot hole and then screw it in again.
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