The 204 will, people use the .17 rem and kill yotes. The 204 will stay there with the 22-250 with light bullets as would a 223 improved. If you need more gun or heavier bullets for longer range id move up to a 243 or 250 cal. I wish i had a 20 tac which is similar to the 204 it would replace my 22-250. Funds permitting it will happen soon.