I just finished a OCL test with a 22-250. I used 37 gns of RL-15 on all cartridges.
#1 touching-.975
#2 -.010 .025
#3 -.25 .050
#4 -.50 .940
As you can tell my rifle likes the bullet about 10 thousands off.
My .223 predator for what ever reason wont shoot unless the bullet has
a BIG jump. Every gun has a sweet spot we just have to find it.
Im a firm believer in finding the sweet spot first then adjust the powder.