It takes a lot of work to get two different bullets to hit at the same point of impact. Even if it does, the down range ballistics are going to vary a great deal.

I've been working with a 375 H&H magnum trying to get a solid bullet to match up with my 300 grain TSX load. I have the TSX set at 2" high at 100 yards and I want to get a solid to hit at 0 at 100 yards with the same scope settings. I've tried about 20 different loads with 3 different solids and 3 kinds of powder but no luck so far.