I am currently building a .260 rem. that I plan on using for dual purpose long range target and long range (for me) hunting. To keep things simple I want to load 140's for both... now here comes the dumb part as I'm fairly new to reloading:

If I load a 140gr Nosler Custom Comp. and a 140gr Nosler Accubond or BT... same case prep, same powder, same primer, seated same depth... will there be a noticeable shift? I understand that each probably has a slightly different BC and SD, which will have an impact; but if I load the 140 Custom Comp. for target shooting and load the AB's or BT's for hunting will it still shoot "minute of deer" at 300 to 400 yards without having to tweak the optics?

Would stand to reason that same mass pushed at the same velocity from the same barrel would have very similar results... or am I way off?