Easy is whatever you train your mind to do. For hunting, i personally don't see how it can get much easier than using minits with a standard dial calibrated for them and working from a 100 yd zero. As for the lighted reticle, I only have one scope having one and im not sure it even works because ive never used it.
But I guess there are some who never turn them off also. You didn't mention the cartridge you will be using, but with a 22" barrel im assuming not very large. That being the case id be using a lower power scope like a 3.5x10 or maybe a 4.5x12.