I agree with what Phranque said "Yes, it is thicker, so your internal volume tends to be a little less, so pressure gets higher sooner....watch your max load, it's typically going to be a little less than book values.

As far as resizing, it is going to be a little tougher the first go-round, but once it's fire formed to your chamber, subsequent resizings are typically easier. And, watch the "extra lube"... more isn't always better. Even though it is thicker, too much lube can still dimple the necks."
I will add only this another way of not deal with the thick brass is after fire forming in your chamber, Neck size those case's and Full length Resize only when you have to.