Does removing a barrel then putting it back on effect the performance of a pet load?

I've got one barrel I'd like to take off to cerekote and another I'd like to take off a different rifle long enough to try a new barrel then return to the current state . I have done extensive load development on both rifles though so I'd rather not have to start from scratch.

Should I expect to have to rework loads or pick up where I left off once I put them back on?