I know they are not meant for it and I am not supporting using a target bullet for hunting. HOWEVER..... Two shots two kills yesterday. 140 gr 6.5 hyb on fairly large buck at about 270 yrds. Dropped him dead as a hammer. Never took another step just straight to the ground. Her buck dropped straight away as well but wiggled around for a couple minutes. Not a huge track of carnage on the way out. In fact I never found entry or exit on my buck. Only blood I saw was from the mouth. That happened once before with 338. Not good expansion but definitely killers if you put them in the right spot.