Having lived and hunted in Arizona, Colorado and Wyoming can attest to the great info posted here.
300 WSM will definitely do the job under proper conditions.
Learn your load, drops, drifts etc and practice them often and in inclimate/unfavorable conditions, decide which shots you will/won't take. Shoot cold, shoot wet, shoot tired- you could realistically be all of the above.
Think about your gear, don't skimp on boots. Look at when you'll be hunting and research weather patterns for that area, averages, extremes etc, be prepared.
Have a blast!! It's a cliche but enjoy the time, the wilderness and the hunt, you'll be better off in the long run that way whether you bag a monster or not.
Best of luck.
BTW where in IA are you?
Bookmarks