They work MUCH better with #12 shot than with #8 or #9 (those will kill a snake but leave it "active" for a while - the #12 seems to make them just go limp instantly).
I either use the CCI/Speer shot cups you can load (blue plastic) or (better because the plastic cups sometimes don't open right and MUCH cheaper) use two crimp on style Hornady gas checks for cast bullets - seat one over the powder charge (cup side up), drop in your shot, seat one cup side down just below the case mouth, over the shot and crimp - works great in everything from 38 Specials to 45 Colts.
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