I can't speak for the 208, but I have used the 155 Amax in my 308 and accidently shot a deer with one (155Amax looks a lot like a 150SST when loaded). It killed the deer DRT, but I wouldn't recommend it. Bullet hit a small amount of bone and blew apart. Deer was roughly 200yds out so it wasn't point blank either.
Since you say "big bull" I assume you are talking Elk, and me personally I would feel tons better with the 210 Hunting VLD over the Amax with all else being equal.
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