I normally start with the bullet just touching the lands until I find a powder and a charge that shows potential, then I start playing with seating depth if need be. I have had some shoot so good that I didn't bother changing depth. Normally I don't end up too far from the lands, most within .010" but one liked it out at .050".
I should also add that in the situation of a very short bullet for a given bore where there is no chance of reaching the lands or anywhere near it, I will normally just start with the base of the bullet just above the bottom of the neck, and if that's too far in then I just play it by feel and pray a lot.
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