Bottom line up front. Not all bullets will shoot well in any specific rifle.
Since I don't know anything about how you go about developing a load, I certainly won't comment on that, except to say that over 100 rounds while working on load development with 5 different powders does not sound like a very large number (certainly not an excessive number) of rounds expended.
Persevere. You may find your accuracy node yet.
I don't mean to be negative, but it could also be that you are simply out of luck as far as pinpoint accuracy with the combination of that particular projectile, those particular powders, and your specific barrel.
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