You know that a lot of this also depend upon the caliber in question. Some overbore and/or small case capacity cartridges are very sensitive to minor changes. The .223 rem and 22/250 fall into this category. The 220 Swift is really sensitive!! Larger bores are not so sensitive, like the 308 diameter bore. I've never been able to get enough powder in a 308 Win case to get a real high pressure problem. That is my experience.
Best regards,
Grit