A fast twist will stabilize any lighter bullet.
I personally dont think you can over stabilize a bullet.
You can over spin them to a point where they explode, but you can slow them down a tad and that works.
Powder depends on the bullet weight.
I like the reloader powders.
Probably reloader 22 for 200 gr bullets.
H4895 and H4350 are both good powders.
H4895 for light bullets but H4895 is too fast for the 300 win mag with heavier bullets, although it might be okay for some reduced loads.
H4350 or IMR 4350 is a good powder for heavier bullets, in the 160-200 gr area.
Use even slower powder for heavier bullets.
Probably best to go to the Hodgdon and Alliant web sites and look at the recommended load data.
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