Where do you live? If you have a chance to try shooting a 375 Ruger without the brake, do it. I've had a Ruger Hawkeye Alaskan in 375 for probably 8 years and recoil isn't as bad as you'd think. It's a pretty solid push but no worse than a 300 Win Mag with 180gr bullets. I have over 1000 rounds through mine and I've never felt like it needed a brake on there.
I appreciate muzzle brakes and have several of them but I hate to use them on hunting guns. Not just because of the noise but because here in WA I end up with stuff getting caught in the ports!
Andrew
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