I have a few ideas.
First you are REALLY bouncing around with powders and bullets without doing much testing. Pick a set of components, THEN work within those parameters. Don't know about "accurateshooter", but picking a website that has A load and using it without work-up is an issue. When you see that the load is too hot, back-off AT LEAST .5 grain, and I personally would do a full grain with the 22-250; not .2.
748 is a bit fast for a 22-250, that is more like 760's realm, or stay with H4895.
Another issue I see is the twist/bullet combo. Why are you shooting light-weight bullets with a heavy-bullet twist??
This very well could be a large part of your problem. The 60gr loads by Hodgdon's numbers, has you very close to the bullets RPM ceiling. For the 52gr bullet, IF (don't have a clue with 748 in the 22-250) you are reaching a modest 3700fps, you are beyond the RPM limit.
MV * 720 / TWIST = RPM. There is NO velocity attainable in a production rifle, that can destroy a bullet. Centrifugal force(RPM) is what destroys bullets!
Hornady 22-cal SP/Vmax bullets have a RPM ceiling of @ 290,000rpm; barrel smoothness dependant.
If you are near the RPM limit without hitting it's destruction stage, you will see VERY poor accuracy; due to an over-stabilization induced "wobble".
Rarely is the max load, the accurate one. Generally for a given weight range, the best accuracy is found in the middle of the velocity range.
Your Vertical stringing can be related to stock issues/ barrel heat as well. High friction from twist, in high pressure loads causes a lot of heat.
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