Use the same COL until you have a load somewhere in the ballpark. - .050" or .040" off the rifling is as good a place as any to start.
I whole grain spread is too much. You could pass the sweet spot & miss it. I usually start about 1/2 to 1gr above the lowest charge. Then a maximum of .5 (1/2gr) jump each time. I make 3 rounds of each. For example:
3 - 48.7gr
3 - 49.2gr
3 - 49.7gr
and so on.
I fire them in 3 round groups & see which group gives me the smallest group. Then, refine what I have. I make a few 3 round batches in .3gr increments. .3gr is the smallest increment I use unless I'm looking to touch up a load for a particular bullet / caliber. Sometimes different brands of brass or primers need a little fine tuning.
I'm sure some of the more "seasoned" reloaders will chime in to enlighten you...
Stay consistant & your ammo will.
Frank in Fla
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