This could be many things.
First of all is the brass. The 338WM/7RM/264WM is NOT a Weatherby case. Are you using Weatherby BRAND cases, or a Weatherby case??
Second, are you sure that your primers are good? Are they seated properly?
What is the firing pin protrusion? Have you measured, or changed your firing pin spring?
If you can't get ignition, it's kind of hard to fire form...
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