According to QuickLOAD, with a 55 V-Max, a reduction of 3 inches of barrel would drop velocity closer to 80 fps.
In my model 11 VT, that I got at an incredible inventory reduction sale, shoots Berger 52 grain FB #22408 and Sierra 52 grain SMK FB #1400 better than the 52 gr SMKs HPBT #1410.
The flat base bullets should still be good at 200 yards.
Most Savage .22-250s have a 1:12 twist. Mine does.
The original .22-250s mostly were 1:14 twist. I have an old Remington 700 with that twist and it would never shoot bullets heavier than 55 grains accurately.
But it would shoot 40 grain Nosler BTs like a laser at 4000 to 4100 fps. They were like grenades on prairie dogs.
I think Savage makes one upscale model 12 in .22-250 with a 1:7 twist.
To get that barrel twist, that would be what I would consider a barrel change to consider.
The 1:12 still doesn't stabilize the 69 and 77 grain bullets that I have found to be really accurate in my .223s.
I would love to be able to shoot the heavier bullets in my .22-250s.