30-06 1:10 pointers?

Just picked up a 22" 1:10 30-06 barrel.

Looking to use this for deer hunting out to +/- 300 yards.

Have H4350, IMR4350, IMR3031, thinking of picking up some 4064 and/or Varget.

Am planning to use 15-165gr bullets, Hornady and Sierras have performed well for me in the past.

That being said anyone have any suggestions? Every barrel is different of course, work up loads safely etc- just looking to get an idea of what has worked well for others with similar combos so I can narrow down a few places to start.

Thanks, Matt.

I have several 30-06s that love IMR 4350 with 165/168gr Sierra Game kings. Yup Game kings. My best loads are at max of 57gr. and I use CCI BR2 primers in Winchester brass jammed in the lands.

Thanks for the reply- have had great success with the game kings.