Lclevenger,
The .22-250 has a larger volume brass than the .223/5.56x45. That changes the dynamics of the powder choices.
I have also found that the slower powders that are mainstays for the .308 also shoot best in the .22-250.
I just about wore out my original Remington 700 in .22-250. The old .22-250s had 1:14 twists that pretty much restricted the bullets to 55 grains and under.
I shot about 5000 rounds through that old rifle and it is about shot out so I replaced it with a 11 VT that I got on an incredible sale.
It shoots about 23% smaller groups with the same bullets but I don't have a lot of data to prove it.
I bought to 6.5mm Creedmoor Savages at just about the same time and got captured by 6.5mm CM's accuracy.
As you already found out, you can really push light bullets to incredible velocities out of a .22-250..
I regularly shot 40 grain Nosler Ballistic tips between 4,000 and 4,100 fps and they were like grenades on prairie dogs.
I think you'll have fun with your .22-250 and the 1:12 twist will let you try some heavier bullets.
I tried up to 60 grains in my 1:14 twist but, while it appeared to stabilize them, they didn't shoot accurately.
My old Remington shot the 52 and 53 grain bullets the best and it really liked the 52 gr flat base Berger #22408 and Sierra 53 gr flat base SMK.
My new Savage also liked them the best but I haven't tried anything heavier.
I expect it to do well with the 55 Berger FB #22410 also but I haven't gotten around to trying them yet.